Royal Society of Chemistry

2021-11-10 03:29:22 By : Mr. Peter Wang

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Scientists have discovered that the Miller-Urey "primitive soup" experiment has been carried out in borosilicate flasks, which is a bit lucky because glass promotes the formation of amino acids, peptides and nucleobases.

In 1952, doctoral student Stanley Miller and doctoral supervisor Harold Urey conducted a classic experiment that would later become a scientist, trying to find out how simple compounds become molecules of life. The two designed a device designed to simulate conditions on Earth 4 billion years ago, combining water, methane, hydrogen and ammonia. Then, they created an artificial lightning storm in the flask, and an electric arc was created between the two electrodes.

What Miller and Yuri might not have imagined is that, as researchers in Spain and Italy have now discovered, glass flasks seem to be a key component of the reaction. They performed the reaction in an ordinary borosilicate glass reactor, a Teflon reactor, and a Teflon reactor containing borosilicate glass flakes in water.

Source: © Reuters/Alamy Stock Photo

Stanley Miller and the equipment in his famous experiment in 1952 simulated conditions thought to have been found on the early Earth. Recent studies have shown that glass reaction vessels play their own role in the chemical reactions that take place in them 

Only when run in glassware does the reaction produce a brown broth containing at least 52 organic compounds. In particular, dipeptides, certain amino acids, dicarboxylic acids, polycyclic aromatic hydrocarbons, and a set of biological nucleobases are more effective in glass containers or are formed only in glass containers-when glass fragments are added to a plastic flask, they are formed To a lesser extent. Although it is not clear exactly how glass promotes reactivity, it may be related to surface silanol groups and trace amounts of metal released from the glass into the solution.

In the decades since 1952, there has been evidence that the gas mixture used in the reaction may not represent the early atmosphere of the early Earth after all. Nevertheless, the Spanish-Italian team stated that Miller and Yuri may have unknowingly simulated the effects of rocks and minerals by reacting in a borosilicate flask. The origin is very important.

J Criado-Reyes et al., Sci. Representative, 2021, 11, 21009 (DOI: 10.1038/s41598-021-00235-4)

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